A mathematical model of the tumour growth along a blood vessel is proposed. The model employs the mixture theory approach to describe a tissue which consists of cells, extra-cellular matrix and liquid. The growing tumour tissue is supposed to be surrounded by the host tissue. Tumours where complete xydation of glucose prevails are considered. Special attention is paid to consistent description of oxygen consumption and growth processes based on the energy balance. A finite difference numerical method is proposed. The level set method is used to track an interface between the tissues. The simulations show localization of the tumour within a limited distance from the vessels and constant expansion velocity along the vessels.

Mathematical model of tumour cord growth along the source of nutrient / Astanin, Sergey; Tosin, Andrea. - In: MATHEMATICAL MODELLING OF NATURAL PHENOMENA. - ISSN 0973-5348. - STAMPA. - 2:3(2007), pp. 153-177. [10.1051/mmnp:2007007]

Mathematical model of tumour cord growth along the source of nutrient

ASTANIN, SERGEY;TOSIN, ANDREA
2007

Abstract

A mathematical model of the tumour growth along a blood vessel is proposed. The model employs the mixture theory approach to describe a tissue which consists of cells, extra-cellular matrix and liquid. The growing tumour tissue is supposed to be surrounded by the host tissue. Tumours where complete xydation of glucose prevails are considered. Special attention is paid to consistent description of oxygen consumption and growth processes based on the energy balance. A finite difference numerical method is proposed. The level set method is used to track an interface between the tissues. The simulations show localization of the tumour within a limited distance from the vessels and constant expansion velocity along the vessels.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11583/1867326
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo